|
|
Equipment and Services
The EPR Core has an array of multifrequency EPR spectrometers and resonator designs capable of measuring samples that range in size from molecules to man. In vitro measurements of free radicals can be made in aqueous solutions or in tissues with volumes as small as 50 uL. Short-lived free radicals of "reaction oxygen species" can be determined using stabilizer molecules called spin traps. Free radical measurements and imaging can also be performed in intact tissues, organs and the whole-bodies of small animals (mice and rats) using low-frequency (300 MHz-1200 MHz) spectrometers. The Core also has the capability for high-resolution (0.1 mmHg) oxygen measurements, in vivo. Repeated measurements (over days to weeks) can be made from a specific site of the animal/organ/tissue using implantable micro/nanoparticulate oximetry probes. |
|
 |
